About Paul
A UX designer adept in interaction design, user research, and product design.
I'm Paul Mangiamele—a scientist-designer hybrid who ships AI products that scale to millions.
Built 4 AI products at AWS in 3.5 years. As AI Product Design Leader for Health AI, I transform how life sciences and healthcare organizations leverage AI. My systems process 10,000+ clinical queries daily and serve 5,000+ biopharma users, reducing prototyping cycles by 82% and increasing adoption by 38%.
Not your typical designer. With a PhD in HCI, 10+ years as a wet lab scientist, and 18+ years shipping production code, I speak the language of researchers, engineers, and executives. I've built RAG systems before RAG was cool (2017), shipped FDA-cleared products to 500+ hospitals, and founded a genomics platform serving 200+ institutions.
When I'm not designing the future of enterprise software, you'll find me restoring vintage motorcycles, shaping surfboards, or exploring San Francisco with my dog Calvin. These hands-on pursuits inform my design philosophy: the best solutions come from understanding materials, processes, and people at a fundamental level.
Expertise & Background
Scientific Foundation
PhD in HCI with deep expertise in life sciences, genomics, and computational biology. Published researcher with lab bench experience.
Design Leadership
18+ years leading UX design for complex enterprise and healthcare products. From prototypes to FDA-cleared products serving 500+ hospitals.
Hands-On Builder
From code to motorcycles to surfboards—I believe in understanding things from the ground up. This maker mindset informs every design decision.